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Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study

Parsa, Afshin, Kanetsky, Peter A., Xiao, Rui, Gupta, Jayanta, Mitra, Nandita, Limou, Sophie, Xie, Dawei, Xu, Huichun, Anderson, Amanda Hyre, Ojo, Akinlolu, Kusek, John W., Lora, Claudia M., Hamm, L. Lee, He, Jiang, Sandholm, Niina , Jeff, Janina, Raj, Dominic E., Böger, Carsten A., Bottinger, Erwin, Salimi, Shabnam, Parekh, Rulan S., Adler, Sharon G., Langefeld, Carl D., Bowden, Donald W., Groop, Per-Henrik, Forsblom, Carol, Freedman, Barry I., Lipkowitz, Michael, Fox, Caroline S., Winkler, Cheryl A. and Feldman, Harold I. (2016) Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study. Journal of the American Society of Nephrology 28 (3), pp. 923-934.

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Other URL: http://doi.org/10.1681/ASN.2015101152


Abstract

The rate of decline of renal function varies significantly among individuals with CKD. To understand better the contribution of genetics to CKD progression, we performed a genome-wide association study among participants in the Chronic Renal Insufficiency Cohort Study. Our outcome of interest was CKD progression measured as change in eGFR over time among 1331 blacks and 1476 whites with CKD. We ...

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Item type:Article
Date:2016
Institutions:Medicine > Abteilung für Nephrologie
Identification Number:
ValueType
10.1681/ASN.2015101152DOI
Keywords:CHRONIC KIDNEY-DISEASE; DIABETIC-NEPHROPATHY; DESIGN; GENES; HCARG; SET; PROTEINURIA; COMPONENTS; AMERICANS; VARIANTS;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38671
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