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Periosteum tissue engineering in an orthotopic in vivo platform

Baldwin, J.G., Wagner, F., Martine, L.C. , Holzapfel, B.M., Theodoropoulos, C., Bas, O. , Savi, F.M., Werner, C. , De-Juan-Pardo, E.M. and Hutmacher, D.W. (2017) Periosteum tissue engineering in an orthotopic in vivo platform. Biomaterials 121, pp. 193-204.

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Other URL: http://doi.org/10.1016/j.biomaterials.2016.11.016


The periosteum plays a critical role in bone homeostasis and regeneration. It contains a vascular component that provides vital blood supply to the cortical bone and an osteogenic niche that acts as a source of bone-forming cells. Periosteal grafts have shown promise in the regeneration of critical size defects, however their limited availability restricts their widespread clinical application. ...


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Item type:Article
Institutions:Medicine > Lehrstuhl für Orthopädie
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Keywords:MESENCHYMAL STEM-CELLS; ACELLULAR DERMAL MATRIX; BLOOD-VESSELS; BONE; FRACTURE; RECEPTOR; VASCULATURE; EXPRESSION; SCAFFOLDS; MICE; Periosteum; Tissue engineering & regenerative medicine; Melt electrospinning writing; Star-PEG heparin hydrogel; Mesenchymal stem cells; Human umbilical vein endothelial cells
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38682
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