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Granulocytapheresis with modified fluid gelatin versus high-molecular-weight hydroxyethyl starch: a matched-pair analysis

Dullinger, Katharina ; Pamler, Irene ; Brosig, Andreas ; Mohrez, Morad ; Hähnel, Viola ; Offner, Robert ; Dormann, Frauke ; Becke, Christine ; Holler, Ernst ; Ahrens, Norbert


BACKGROUND: Granulocyte apheresis requires a sedimentation agent. Usually, hydroxyethyl starch (HES) is administered to donors for this purpose and, as granulocyte concentrate (GC) ingredient, also to patients. Authorities recently recommended suspending market authorizations for starch-containing products due to side effects. Therefore, we tested the efficacy of modified fluid gelatin (MFG, ...


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