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WNT5A: a motility-promoting factor in Hodgkin lymphoma

Linke, F , Zaunig, S, Nietert, M M , von Bonin, F, Lutz, S, Dullin, C , Janovská, P, Beissbarth, T, Alves, F, Klapper, W, Bryja, V, Pukrop, T, Trümper, L, Wilting, J and Kube, D (2017) WNT5A: a motility-promoting factor in Hodgkin lymphoma. Oncogene 36 (1), pp. 13-23.

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Other URL: http://doi.org/10.1038/onc.2016.183


Abstract

Classical Hodgkin lymphoma (cHL) has a typical clinical manifestation, with dissemination involving functionally neighboring lymph nodes. The factors involved in the spread of lymphoma cells are poorly understood. Here we show that cHL cell lines migrate with higher rates compared with non -Hodgkin lymphoma cell lines. cHL cell migration, invasion and adhesion depend on autocrine WNT signaling as ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
ValueType
10.1038/onc.2016.183DOI
Keywords:CELL POLARITY PATHWAY; REED-STERNBERG CELLS; CHRONIC LYMPHOCYTIC-LEUKEMIA; BETA-CATENIN; DISHEVELLED PHOSPHORYLATION; SIGNALING PATHWAYS; GENE-EXPRESSION; BREAST-CANCER; MIGRATION; PROLIFERATION;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38816
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