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Annexin A6 regulates adipocyte lipid storage and adiponectin release

Krautbauer, Sabrina, Haberl, Elisabeth M., Eisinger, Kristina, Pohl, Rebekka, Rein-Fischboeck, Lisa, Rentero, Carles, Alvarez-Guaita, Anna, Enrich, Carlos, Grewal, Thomas, Buechler, Christa and Neumeier, Markus (2017) Annexin A6 regulates adipocyte lipid storage and adiponectin release. Molecular and Cellular Endocrinology 439, pp. 419-430.

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Other URL: http://doi.org/10.1016/j.mce.2016.09.033


Abstract

Lipid storage and adipokine secretion are critical features of adipocytes. Annexin A6 (AnxA6) is a lipid binding protein regulating secretory pathways and its role in adiponectin release was examined. The siRNA-mediated AnxA6 knock-down in 3T3-L1 preadipocytes impaired proliferation, and differentiation of AnxA6-depleted cells to mature adipocytes was associated with higher soluble adiponectin ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1016/j.mce.2016.09.033DOI
Keywords:ADIPOSE-TISSUE DEPOTS; CHOLESTEROL TRANSPORT; ADIPOKINE SECRETION; 3T3-L1 CELLS; VISCERAL FAT; IN-VITRO; OBESITY; INSULIN; MICE; ADIPOGENESIS; Intra-abdominal fat; Obesity; Lipid droplet; Lipolysis; Adipokine
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38817
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