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Inflammation Is an Important Covariate for the Crosstalk of Sleep and the HPA Axis in Rheumatoid Arthritis

Straub, Rainer H. , Detert, Jaqueline, Dziurla, René, Fietze, Ingo, Loeschmann, Peter-Andreas, Burmester, Gerd R. and Buttgereit, Frank (2017) Inflammation Is an Important Covariate for the Crosstalk of Sleep and the HPA Axis in Rheumatoid Arthritis. Neuroimmunomodulation 24 (1), pp. 11-20.

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Other URL: http://doi.org/10.1159/000475714


Abstract

Rheumatoid arthritis (RA) patients have sleep problems, and inflammation influences sleep. We demonstrated that sleep quality improves during intensified treatment with methotrexate (MTX) or etanercept (ETA). Since the hypothalamicpituitary-adrenal (HPA) axis is involved in sleep regulation, this study investigated the interrelation between sleep parameters, inflammation as objectified by ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1159/000475714DOI
Keywords:CORTICOTROPIN-RELEASING HORMONE; NECROSIS FACTOR THERAPY; PITUITARY-ADRENAL AXIS; IMMUNE-SYSTEM; CIRCADIAN-RHYTHM; CORTISOL; DEPRESSION; FATIGUE; QUALITY; NEUROENDOCRINE; Rheumatoid arthritis; Sleep; Intensive therapy; Anti-TNF therapy; Cortisol; Hypothalamic-pituitary-adrenal axis
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38857
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