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Mapping the secretome of human chondrogenic progenitor cells with mass spectrometry

Batschkus, Sarah, Atanassov, Ilian, Lenz, Christof, Meyer-Marcotty, Philipp, Cingöz, Gökhan, Kirschneck, Christian, Urlaub, Henning and Miosge, Nicolai (2017) Mapping the secretome of human chondrogenic progenitor cells with mass spectrometry. Annals of Anatomy - Anatomischer Anzeiger 212, pp. 4-10.

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Other URL: http://doi.org/10.1016/j.aanat.2017.03.003


Abstract

Tissue engineering offers promising perspectives in the therapy of osteoarthritis. In the context of cell based therapy, chondrogenic progenitor cells (CPCs) may be used to regenerate defects in cartilage tissue. An in-depth characterization of the secretome of CPCs is a prerequisite to this approach. In this study, a method was developed for the qualitative and quantitative analysis of the ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Kieferorthopädie
Identification Number:
ValueType
10.1016/j.aanat.2017.03.003DOI
Keywords:ARTICULAR CHONDROCYTES; QUANTITATIVE PROTEOMICS; OSTEOARTHRITIS; QUANTIFICATION; MECHANISMS; EXPRESSION; PROTEIN-1; COMPLEXES; CULTURE; TISSUE; Osteoarthritis; Secretome; Chondrogenic progenitor cells; Mass spectrometry; Tissue engineering
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38869
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