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Mapping the secretome of human chondrogenic progenitor cells with mass spectrometry

Batschkus, Sarah ; Atanassov, Ilian ; Lenz, Christof ; Meyer-Marcotty, Philipp ; Cingöz, Gökhan ; Kirschneck, Christian ; Urlaub, Henning ; Miosge, Nicolai


Tissue engineering offers promising perspectives in the therapy of osteoarthritis. In the context of cell based therapy, chondrogenic progenitor cells (CPCs) may be used to regenerate defects in cartilage tissue. An in-depth characterization of the secretome of CPCs is a prerequisite to this approach. In this study, a method was developed for the qualitative and quantitative analysis of the ...


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