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Ror2 Signaling and Its Relevance in Breast Cancer Progression

Bayerlová, Michaela, Menck, Kerstin , Klemm, Florian, Wolff, Alexander, Pukrop, Tobias, Binder, Claudia, Beißbarth, Tim and Bleckmann, Annalen (2017) Ror2 Signaling and Its Relevance in Breast Cancer Progression. Frontiers in Oncology 7.

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Other URL: http://doi.org/10.3389/fonc.2017.00135

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Breast cancer is a heterogeneous disease and has been classified into five molecular subtypes based on gene expression profiles. Signaling processes linked to different breast cancer molecular subtypes and different clinical outcomes are still poorly understood. Aberrant regulation of Wnt signaling has been implicated in breast cancer progression. In particular Ror1/2 receptors and several other ...


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Item type:Article
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
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Keywords:TYROSINE KINASE ROR2; GENE-EXPRESSION DATA; CELL-MIGRATION; BETA-CATENIN; DATA SETS; RECEPTOR; SUBTYPES; WNT; PATHWAY; GENOME; Wnt signaling; Ror2; network integration; module; breast cancer; metastasis
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38873
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