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IL-17-producing γδ T cells switch migratory patterns between resting and activated states

McKenzie, Duncan R., Kara, Ervin E., Bastow, Cameron R., Tyllis, Timona S. , Fenix, Kevin A. , Gregor, Carly E., Wilson, Jasmine J., Babb, Rachelle, Paton, James C., Kallies, Axel, Nutt, Stephen L. , Brüstle, Anne, Mack, Matthias, Comerford, Iain and McColl, Shaun R. (2017) IL-17-producing γδ T cells switch migratory patterns between resting and activated states. Nature Communications 8, p. 15632.

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Other URL: http://doi.org/10.1038/ncomms15632

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Interleukin 17-producing gamma delta T (gamma delta T17) cells have unconventional trafficking characteristics, residing in mucocutaneous tissues but also homing into inflamed tissues via circulation. Despite being fundamental to gamma delta T17-driven early protective immunity and exacerbation of autoimmunity and cancer, migratory cues controlling gamma delta T17 cell positioning in barrier ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
10.1038/ncomms15632DOI
Keywords:EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; PSORIASIFORM SKIN INFLAMMATION; T-CELL SUBSETS; DENDRITIC CELLS; INTERFERON-GAMMA; LYMPH-NODES; TH17 CELLS; DIFFERENTIATION; PROMOTE; ARTHRITIS;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38903
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