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High Androgen Receptor mRNA Expression Is Independently Associated with Prolonged Cancer-Specific and Recurrence-Free Survival in Stage T1 Bladder Cancer

Sikic, Danijel ; Breyer, Johannes ; Hartmann, Arndt ; Burger, Maximilian ; Erben, Philipp ; Denzinger, Stefan ; Eckstein, Markus ; Stöhr, Robert ; Wach, Sven ; Wullich, Bernd ; Keck, Bastian ; Wirtz, Ralph M. ; Otto, Wolfgang



Abstract

INTRODUCTION: High-risk non-muscle-invasive bladder cancer (NMIBC) remains challenging given the high probability of progression. Given that the androgen receptor (AR) has been discussed as a possible factor in the development and progression of bladder cancer, we investigated the predictive value of AR in stage pT1 NMIBC. MATERIALS AND METHODS: We retrospectively analyzed the clinical data and ...

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