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Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis

Weismüller, Tobias J., Trivedi, Palak J., Bergquist, Annika, Imam, Mohamad, Lenzen, Henrike, Ponsioen, Cyriel Y., Holm, Kristian, Gotthardt, Daniel, Färkkilä, Martti A., Marschall, Hanns-Ulrich, Thorburn, Douglas, Weersma, Rinse K., Fevery, Johan, Mueller, Tobias, Chazouillères, Olivier, Schulze, Kornelius, Lazaridis, Konstantinos N., Almer, Sven, Pereira, Stephen P. , Levy, Cynthia, Mason, Andrew, Naess, Sigrid, Bowlus, Christopher L., Floreani, Annarosa, Halilbasic, Emina, Yimam, Kidist K., Milkiewicz, Piotr , Beuers, Ulrich, Huynh, Dep K., Pares, Albert , Manser, Christine N., Dalekos, George N., Eksteen, Bertus, Invernizzi, Pietro, Berg, Christoph P., Kirchner, Gabi I., Sarrazin, Christoph, Zimmer, Vincent , Fabris, Luca, Braun, Felix, Marzioni, Marco, Juran, Brian D., Said, Karouk, Rupp, Christian, Jokelainen, Kalle, Benito de Valle, Maria, Saffioti, Francesca , Cheung, Angela, Trauner, Michael, Schramm, Christoph, Chapman, Roger W., Karlsen, Tom H., Schrumpf, Erik, Strassburg, Christian P., Manns, Michael P., Lindor, Keith D., Hirschfield, Gideon M. , Hansen, Bettina E. and Boberg, Kirsten M. (2017) Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis. Gastroenterology 152 (8), 1975-1984.e8.

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Other URL: http://doi.org/10.1053/j.gastro.2017.02.038


Abstract

BACKGROUND & AIMS: Primary sclerosing cholangitis (PSC) is an orphan hepatobiliary disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of disease progression based on distinct clinical phenotypes in a large international cohort of patients with PSC. METHODS: We performed a retrospective outcome analysis of patients diagnosed with PSC from 1980 through 2010 at ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1053/j.gastro.2017.02.038DOI
Keywords:DOSE URSODEOXYCHOLIC ACID; PRIMARY BILIARY-CIRRHOSIS; GENOME-WIDE ASSOCIATION; POPULATION-BASED COHORT; ULCERATIVE-COLITIS; NATURAL-HISTORY; RISK-FACTORS; CLINICAL PRESENTATION; CROHNS-DISEASE; SINGLE-CENTER; Risk Stratification; Immune-Mediated Liver Disease; Autoimmune Liver Disease; Cholestasis
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38939
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