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The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model

Bocuk, Derya, Wolff, Alexander, Krause, Petra, Salinas, Gabriela, Bleckmann, Annalen, Hackl, Christina, Beissbarth, Tim and Koenig, Sarah (2017) The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model. BMC Cancer 17 (1).

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Other URL: http://doi.org/10.1186/s12885-017-3342-1

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Background: Colorectal cancer (CRC) is the second leading cause of cancer-related death in men and women. Systemic disease with metastatic spread to distant sites such as the liver reduces the survival rate considerably. The aim of this study was to investigate the changes in gene expression that occur on invasion and expansion of CRC cells when forming metastases in the liver. Methods: The ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Chirurgie
Identification Number:
ValueType
10.1186/s12885-017-3342-1DOI
Keywords:COLON-CANCER; PROGRESSION; MICROENVIRONMENT; BEVACIZUMAB; SIGNATURE; SURVIVAL; THERAPY; FOLFIRI; GENOME; GROWTH; Colorectal cancer (CRC); RNA-sequencing; Gene expression; Liver metastasis
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38995
Owner only: item control page
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