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Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection

Channappanavar, Rudragouda, Fett, Craig, Mack, Matthias, Ten Eyck, Patrick P. , Meyerholz, David K. and Perlman, Stanley (2017) Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection. The Journal of Immunology 198 (10), pp. 4046-4053.

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Other URL: http://doi.org/10.4049/jimmunol.1601896


Abstract

Pathogenic human coronaviruses (CoVs), such as the severe acute respiratory syndrome (SARS)-CoV and the Middle East respiratory syndrome-CoV, cause acute respiratory illness. Epidemiological data from the 2002-2003 SARS epidemic and recent Middle East respiratory syndrome outbreak indicate that there may be sex-dependent differences in disease outcomes. To investigate these differences, we ...

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Item type:Article
Date:2017
Institutions:Medicine > Abteilung für Nephrologie
Identification Number:
ValueType
10.4049/jimmunol.1601896DOI
Keywords:PLASMACYTOID DENDRITIC CELLS; INFLAMMATORY CYTOKINES; MEDIATED RESPONSE; INNATE IMMUNITY; LUNG PATHOLOGY; I INTERFERON; BALB/C MICE; SARS; VIRUS; PATHOGENESIS;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38997
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