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Flavin-containing enzymes as a source of reactive oxygen species in HEMA-induced apoptosis

Schweikl, Helmut, Gallorini, Marialucia , Forstner, Markus, Petzel, Christine, Bolay, Carola, Hiller, Karl-Anton, Cataldi, Amelia, Krifka, Stephanie and Buchalla, Wolfgang (2017) Flavin-containing enzymes as a source of reactive oxygen species in HEMA-induced apoptosis. Dental Materials 33 (5), e255-e271.

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Other URL: http://doi.org/10.1016/j.dental.2017.01.014


Abstract

Objective. Oxidative stress induced by compounds of dental composites like 2-hydroxyethyl methacrylate (HEMA) due to excess formation of reactive oxygen species (ROS) disturbs vital cell functions leading to apoptosis. The sources of ROS in cells exposed to resin monomers are unknown. The present study investigates functions of flavin-containing ROS and RNS (reactive nitrogen species) producing ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie
Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie > Prof. Dr. rer. nat. Helmut Schweikl
Identification Number:
ValueType
10.1016/j.dental.2017.01.014DOI
Keywords:TRIETHYLENE GLYCOL DIMETHACRYLATE; OXIDATIVE STRESS; NADPH OXIDASES; HYDROGEN-PEROXIDE; NITRIC-OXIDE; IN-VITRO; DIHYDRORHODAMINE 123; CELLS; SUPEROXIDE; PEROXYNITRITE; Resin monomer; HEMA; Reactive oxygen species; Flavin-containing enzymes; Apoptosis
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39024
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