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Increased extracellular water measured by bioimpedance and by increased serum levels of atrial natriuretic peptide in RA patients—signs of volume overload

Straub, Rainer H. ; Ehrenstein, Boris ; Günther, Florian ; Rauch, Luise ; Trendafilova, Nadezhda ; Boschiero, Dario ; Grifka, Joachim ; Fleck, Martin



Zusammenfassung

The aim of the study is to investigate water compartments in patients with rheumatoid arthritis (RA). Acute inflammatory episodes such as infection stimulate water retention, chiefly implemented by the sympathetic nervous system (SNS) and hypothalamic-pituitary-adrenal (HPA) axis. This is an important compensatory mechanism due to expected water loss (sweating etc.). Since SNS and HPA axis are ...

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