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The hedgehog-signaling pathway is repressed during the osteogenic differentiation of dental follicle cells

Morsczeck, C., Reck, A. and Beck, H. C. (2017) The hedgehog-signaling pathway is repressed during the osteogenic differentiation of dental follicle cells. Molecular and Cellular Biochemistry 428 (1-2), pp. 79-86.

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Other URL: http://doi.org/10.1007/s11010-016-2918-4


Abstract

Dental follicle stem cells (DFCs) are precursor cells of alveolar osteoblasts, and previous studies have shown that the growth factor bone morphogenetic protein (BMP)2 induces the osteogenic differentiation of DFCs. However, the molecular mechanism down-stream of the induction of the osteogenic differentiation by BMP2 remains elusive. We investigated therefore the phosphoproteome of DFCs after ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Identification Number:
ValueType
10.1007/s11010-016-2918-4DOI
Keywords:PRECURSOR CELLS; ALKALINE-PHOSPHATASE; STEM-CELLS; TOOTH ROOT; EXPRESSION; PROTEIN; CHALLENGES; MOUSE; TEETH; BONE; Hedgehog-signaling pathway; Dental follicle cells; Osteogenic differentiation; Periodontium; Bone morphogenetic protein
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39129
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