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Role of hepatic Annexin A6 in fatty acid-induced lipid droplet formation

Cairns, Rose , Alvarez-Guaita, Anna, Martínez-Saludes, Inés, Wason, Sundeep J., Hanh, Jacky, Nagarajan, Shilpa R., Hosseini-Beheshti, Elham, Monastyrskaya, Katia, Hoy, Andrew J., Buechler, Christa, Enrich, Carlos, Rentero, Carles and Grewal, Thomas (2017) Role of hepatic Annexin A6 in fatty acid-induced lipid droplet formation. Experimental Cell Research 358 (2), pp. 397-410.

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Other URL: http://doi.org/10.1016/j.yexcr.2017.07.015


Abstract

Annexin A6 (AnxA6) has been implicated in the regulation of endo-/exocytic pathways, cholesterol transport, and the formation of multifactorial signaling complexes in many different cell types. More recently, AnxA6 has also been linked to triglyceride storage in adipocytes. Here we investigated the potential role of AnxA6 in fatty acid (FA) induced lipid droplet (LD) formation in hepatocytes. ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1016/j.yexcr.2017.07.015DOI
Keywords:CHOLESTEROL TRANSPORT; PHOSPHOLIPASE A(2); PROTEINS; MICE; DEGRADATION; TRAFFICKING; AUTOPHAGY; GOLGI; LIVER; VI; Annexin A6; Lipid droplets; Fatty acid; Hepatocytes; Cytoplasmic phospholipase A2
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39170
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