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Intraoperative clinical testing overestimates the therapeutic window of the permanent DBS electrode in the subthalamic nucleus

Blume, Josefine ; Schlaier, J. ; Rothenfußer, E. ; Anthofer, J. ; Zeman, F. ; Brawanski, A. ; Bogdahn, U. ; Lange, M.


Intraoperative test stimulation is established to optimize target localization in STN DBS, but requires a time-consuming awake surgery in off-medication state. The aim of this study was to compare the thresholds of stimulation-induced effects of test stimulation and the permanent electrode. Fifty-nine PD patients receiving bilateral STN DBS were clinically examined with stepwise increasing ...


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