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Immunoassay screening in urine for synthetic cannabinoids – an evaluation of the diagnostic efficiency

Franz, Florian ; Angerer, Verena ; Jechle, Hanna ; Pegoro, Melanie ; Ertl, Harald ; Weinfurtner, Georg ; Janele, David ; Schlögl, Christian ; Friedl, Matthias ; Gerl, Stefan ; Mielke, Reinhard ; Zehnle, Ralf ; Wagner, Matthias ; Moosmann, Bjoern ; Auwärter, Volker



Abstract

Background: The abuse of synthetic cannabinoids (SCs) as presumed legal alternative to cannabis poses a great risk to public health. For economic reasons many laboratories use immunoassays (IAs) to screen for these substances in urine. However, the structural diversity and high potency of these designer drugs places high demands on IAs regarding cross-reactivity of the antibodies used and ...

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