Go to content
UR Home

Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma

Schumacher, Sarah ; Bartenhagen, Christoph ; Hoffmann, Martin ; Will, Daniel ; Fischer, Johannes C. ; Baldus, Stephan E. ; Vay, Christian ; Fluegen, Georg ; Dizdar, Levent ; Vallböhmer, Daniel ; Klein, Christoph A. ; Knoefel, Wolfram T. ; Stoecklein, Nikolas H. ; Möhlendick, Birte


Background: Chromosomal instability (CIN) has repeatedly been identified as a prognostic marker. Here we evaluated the percentage of aberrant genome per cell (PAG) as a measure of CIN in single disseminated tumour cells (DTC) isolated from patients with operable oesophageal adenocarcinoma (EAC), to assess the impact of CINhigh DTCs on prognosis. Methods: We isolated CK18(positive) DTCs from bone ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons