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Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men

Zimny, Sebastian, Pohl, Rebekka, Rein-Fischboeck, Lisa, Haberl, Elisabeth M., Krautbauer, Sabrina, Weiss, Thomas S. and Buechler, Christa (2017) Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men. Experimental and Molecular Pathology 103 (1), pp. 1-8.

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Other URL: http://doi.org/10.1016/j.yexmp.2017.06.001


Abstract

Chemokine (CC-motif) receptor-like 2 (CCRL2) is a decoy receptor and regulates the local responses of the chemokine chemerin. Recently our group has shown that the functional chemerin receptor, chemokine-like receptor 1 (CMKLR1), correlates with fibrosis and non-alcoholic steatohepatitis (NASH) score in males only. In our current study, we wanted to know whether CCRL2 shows similar correlations ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Kinder- und Jugendmedizin
Identification Number:
ValueType
10.1016/j.yexmp.2017.06.001DOI
Keywords:FATTY LIVER-DISEASE; GLUCOSE-INTOLERANCE; ENDOTHELIAL-CELLS; ATHEROGENIC DIET; GENE-EXPRESSION; CHEMERIN; CCRL2; INFLAMMATION; OBESITY; POLARIZATION; Chemerin; Hepatocytes; Inflammation; TNF; Type 2 diabetes
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39285
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