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Drosophila Rhodopsin 7 can partially replace the structural role of Rhodopsin 1, but not its physiological function

Grebler, Rudi, Kistenpfennig, Christa, Rieger, Dirk , Bentrop, Joachim, Schneuwly, Stephan, Senthilan, Pingkalai R. and Helfrich-Förster, Charlotte (2017) Drosophila Rhodopsin 7 can partially replace the structural role of Rhodopsin 1, but not its physiological function. Journal of Comparative Physiology A 203 (8), pp. 649-659.

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Other URL: http://doi.org/10.1007/s00359-017-1182-8


Abstract

Rhodopsin 7 (Rh7), a new invertebrate Rhodopsin gene, was discovered in the genome of Drosophila melanogaster in 2000 and thought to encode for a functional Rhodopsin protein. Indeed, Rh7 exhibits most hallmarks of the known Rhodopsins, except for the G-protein-activating QAKK motif in the third cytoplasmic loop that is absent in Rh7. Here, we show that Rh7 can partially substitute Rh1 in the ...

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Item type:Article
Date:2017
Institutions:Biology, Preclinical Medicine > Institut für Zoologie > Entwicklungsbiologie (Prof. Dr. Stephan Schneuwly)
Identification Number:
ValueType
10.1007/s00359-017-1182-8DOI
Keywords:RETINAL DEGENERATION; COMPOUND EYE; HETEROLOGOUS EXPRESSION; PHOTORECEPTOR CELLS; ECTOPIC EXPRESSION; MELANOGASTER; OPSIN; GENE; SYSTEM; BLUE; Phototransduction; Electroretinograms; Rhodopsins; Compound eyes; Drosophila melanogaster
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39307
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