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The impact of white matter lesions on the cognitive outcome of subthalamic nucleus deep brain stimulation in Parkinson’s disease

Blume, J. ; Lange, M. ; Rothenfusser, E. ; Doenitz, C. ; Bogdahn, U. ; Brawanski, A. ; Schlaier, J.



Abstract

Objectives: White Matter lesions (WML) are a risk factor for cognitive impairment in Parkinson's disease. There is no clear evidence of reduced general cognitive function after DBS. However, a subgroup of patients develops dementia rapidly after DBS despite careful patient selection processes. The aim of this study was to evaluate the load of WML as a possible risk factor for cognitive decline ...

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