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FOXM1 predicts overall and disease specific survival in muscle-invasive urothelial carcinoma and presents a differential expression between bladder cancer subtypes

Rinaldetti, Sebastien, Wirtz, Ralph Markus, Worst, Thomas Stefan, Eckstein, Markus, Weiss, Cleo Aaron, Breyer, Johannes, Otto, Wolfgang, Bolenz, Christian, Hartmann, Arndt and Erben, Philipp (2017) FOXM1 predicts overall and disease specific survival in muscle-invasive urothelial carcinoma and presents a differential expression between bladder cancer subtypes. Oncotarget 8 (29).

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Other URL: http://doi.org/10.18632/oncotarget.17394


Abstract

Forkhead box M1 (FOXM1) is a late cell cycle gene that plays a crucial role in carcinogenesis and chemotherapeutic drug resistance. In this study, the impact of FOXM1 expression on patient outcome was investigated for the first time in formalin fixed and paraffin embedded (FFPE) samples of chemotherapy naive muscle-invasive bladder cancer (MIBC) patients. Expression analyses were performed on the ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Urologie
Identification Number:
ValueType
10.18632/oncotarget.17394DOI
Keywords:BREAST-CANCER; RADICAL CYSTECTOMY; HEPATOCELLULAR-CARCINOMA; REGULATES EXPRESSION; MEDIATES RESISTANCE; MOLECULAR SUBTYPES; LUMINAL SUBTYPES; GENE-EXPRESSION; POOR-PROGNOSIS; GASTRIC-CANCER; FOXM1; muscle invasive bladder cancer; KI67; subclassification; survival prediction
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39361
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