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Associations of systemic sphingolipids with measures of hepatic function in liver cirrhosis are related to cholesterol

Krautbauer, Sabrina ; Wiest, Reiner ; Liebisch, Gerhard ; Buechler, Christa



Abstract

Lipoprotein particles are composed of various lipid classes including cholesterol and sphingolipids, and are low in serum of patients with liver cirrhosis. Hepatic decompensation is associated with a further decline of lipoproteins. Aim of the present work was to evaluate whether ceramide and sphingomyelin species are similarly changed in patients with liver cirrhosis and whether these variations ...

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