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Scaffold-cell bone engineering in a validated preclinical animal model: precursors vs differentiated cell source

Berner, A., Henkel, J., Woodruff, M. A. , Saifzadeh, S., Kirby, G., Zaiss, S., Gohlke, J., Reichert, J. C., Nerlich, M., Schuetz, M. A. and Hutmacher, D. W. (2015) Scaffold-cell bone engineering in a validated preclinical animal model: precursors vs differentiated cell source. Journal of Tissue Engineering and Regenerative Medicine 11 (7), pp. 2081-2089.

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Other URL: http://doi.org/10.1002/term.2104


Abstract

The properties of osteoblasts (OBs) isolated from the axial skeleton (tOBs) differ from OBs of the orofacial skeleton (mOBs) due to the different embryological origins of the bones. The aim of the study was to assess and compare the regenerative potential of allogenic bone marrow-derived mesenchymal progenitor cells with allogenic tOBs and allogenic mOBs in combination with a mPCL-TCP scaffold in ...

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Item type:Article
Date:2015
Institutions:Medicine > Lehrstuhl für Unfallchirurgie
Identification Number:
ValueType
10.1002/term.2104DOI
Keywords:MESENCHYMAL STEM-CELLS; IMMUNOLOGICAL-PROPERTIES; PROGENITOR CELLS; REGENERATION; CREST; BIOLOGY; GRAFTS; SHEEP; FATE; bone defect; mesenchymal progenitor cells; allogenic cells; osteoblasts; bone tissue engineering; bone regeneration; scaffolds; polycaprolactone
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39411
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