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Longitudinal Diffusion Tensor Imaging-Based Assessment of Tract Alterations: An Application to Amyotrophic Lateral Sclerosis

Baldaranov, Dobri, Khomenko, Andrei, Kobor, Ines, Bogdahn, Ulrich, Gorges, Martin, Kassubek, Jan and Müller, Hans-Peter (2017) Longitudinal Diffusion Tensor Imaging-Based Assessment of Tract Alterations: An Application to Amyotrophic Lateral Sclerosis. Frontiers in Human Neuroscience 11.

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Other URL: http://doi.org/10.3389/fnhum.2017.00567

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Objective: The potential of magnetic resonance imaging (MRI) as a technical biomarker for cerebral microstructural alterations in neurodegenerative diseases is under investigation. In this study, a framework for the longitudinal analysis of diffusion tensor imaging (DTI)-based mapping was applied to the assessment of predefined white matter tracts in amyotrophic lateral sclerosis (ALS), as an ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Neurologie
Identification Number:
ValueType
10.3389/fnhum.2017.00567DOI
Keywords:COLONY-STIMULATING FACTOR; MOTOR-NEURON DISEASES; NEURODEGENERATIVE DISEASES; NEUROIMAGING BIOMARKER; HUMAN BRAIN; PATHOLOGY; MRI; TRACTOGRAPHY; PROPAGATION; PROGRESSION; magnetic resonance imaging; diffusion tensor imaging; neurodegeneration; neurodegenerative disease; DTI metrics
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39475
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