Go to content
UR Home

Toehold-enhanced LNA probes for selective pull down and single-molecule analysis of native chromatin

Hermans, Nicolaas, Huisman, Juriën Jori, Brouwer, Thomas Bauke, Schächner, Christopher, van Heusden, G. Paul H., Griesenbeck, Joachim and van Noort, John (2017) Toehold-enhanced LNA probes for selective pull down and single-molecule analysis of native chromatin. Scientific Reports 7 (1).

Full text not available from this repository.

at publisher (via DOI)

Other URL: http://doi.org/10.1038/s41598-017-16864-7

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

The organization of DNA into chromatin is thought to regulate gene expression in eukaryotes. To study its structure in vitro, there is a need for techniques that can isolate specific chromosomal loci of natively assembled chromatin. Current purification methods often involve chemical cross-linking to preserve the chromatin composition. However, such cross-linking may affect the native structure. ...

plus


Export bibliographical data



Item type:Article
Date:2017
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Dr. Joachim Griesenbeck
Identification Number:
ValueType
10.1038/s41598-017-16864-7DOI
Keywords:LOCKED NUCLEIC-ACIDS; FORCE SPECTROSCOPY; THERMODYNAMIC PARAMETERS; INDIVIDUAL NUCLEOSOMES; DNA-MOLECULES; REVEALS; LOCI; TRANSCRIPTION; PURIFICATION; COMPLEXES;
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39518
Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons