Teusch, Veronika I., Wohlgemuth, Walter A., Hammer, Simone, Piehler, Armin P., Müller-Wille, René, Goessmann, Holger and Uller, Wibke
(2017)
Ethanol-Gel Sclerotherapy of Venous Malformations: Effectiveness and Safety.
American Journal of Roentgenology 209 (6), pp. 1390-1395.
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Other URL: http://doi.org/10.2214/AJR.16.17603
Abstract
OBJECTIVE. In the treatment of venous malformations, ethanol may be administered in a gelified form to increase local effects and reduce systemic ones. The purpose of this prospective study was to evaluate the efficacy and safety of a commercially available viscous ethanol gel in the treatment of venous malformations. SUBJECTS AND METHODS. Thirty-one patients (mean age, 23.4 years; age range, ...
Abstract
OBJECTIVE. In the treatment of venous malformations, ethanol may be administered in a gelified form to increase local effects and reduce systemic ones. The purpose of this prospective study was to evaluate the efficacy and safety of a commercially available viscous ethanol gel in the treatment of venous malformations. SUBJECTS AND METHODS. Thirty-one patients (mean age, 23.4 years; age range, 6.6-46.5 years) with venous malformations were prospectively scheduled for two ethanol-gel sclerotherapy sessions. Venous malformations were located at the lower extremity (n = 18), the upper extremity (n = 9), and the face (n = 4). Questionnaires to assess pain, clinical examinations, professional photographs, and contrast-enhanced MRI of the venous malformations were performed before and after therapy to measure therapy-induced changes. Two experienced radiologists blinded to the examination date and clinical status compared photographs and MR images before and after treatment. RESULTS. A mean of 4.2 mL of ethanol gel were administered per session. The technical success rate was 100%. Clinical success, defined as improvement or resolution of symptoms, was noted in 81% of patients. Mean pain score decreased, and the difference was statistically significant (3.9 vs 3.1, p = 0.005). In 54 treatment sessions where follow-up was available, four minor complications occurred. Comparison of photographs and MR images before and after treatment showed improvement in 35% and 93% of patients, respectively. CONCLUSION. Ethanol gel is an effective and safe sclerosing agent in the treatment of venous malformations.
Export bibliographical data
| Item type: | Article |
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| Date: | 2017 |
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| Institutions: | Medicine > Lehrstuhl für Röntgendiagnostik |
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| Identification Number: | | Value | Type |
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| 10.2214/AJR.16.17603 | DOI |
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| Keywords: | FLOW VASCULAR MALFORMATIONS; CARDIOVASCULAR COLLAPSE; SCLEROSING AGENT; COMPLICATIONS; PARAMETERS; NECK; HEAD; ethanol gel; sclerotherapy; venous malformation |
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| Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine |
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| Status: | Published |
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| Refereed: | Yes, this version has been refereed |
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| Created at the University of Regensburg: | Yes |
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| Item ID: | 39526 |
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