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Dermatopathic lymphadenopathy with Langerhans cell chimerism in graft-versus-host disease of the skin

Kreft, Andreas ; Krümpelmann, Kristina ; Rosenwald, Andreas ; Hollemann, David ; Wagner-Drouet, Eva Maria



Abstract

Dermatopathic lymphadenopathy (DL) is well-known in inflammatory skin disease; however, it has not been reported in graft-versus-host disease (GvHD) after allogeneic stem cell transplantation. Here, we report 2 cases of DL in patients with acute GvHD of the skin and demonstrate complete donor chimerism of Langerhans cells within the lymph nodes.


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