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Fluorescein-Guided Resection of Intramedullary Spinal Cord Tumors: Results from a Preliminary, Multicentric, Retrospective Study

Acerbi, Francesco ; Cavallo, Claudio ; Schebesch, Karl-Michael ; Akçakaya, Mehmet Osman ; de Laurentis, Camilla ; Hamamcioglu, Mustafa Kemal ; Broggi, Morgan ; Brawanski, Alexander ; Falco, Jacopo ; Cordella, Roberto ; Ferroli, Paolo ; Kiris, Talat ; Höhne, Julius


BACKGROUND: Intramedullary spinal cord tumors (IMSCTs) are rare, heterogenous lesions that are usually enhanced on preoperative magnetic resonance imaging (MRI) because of a damaged blood-brain barrier. Sodium fluorescein is a dye that accumulates in areas of the central nervous system with a damaged BBB. Given the pattern of MRI contrast enhancement of the majority of IMSCTs, the use of this ...


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