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DHRS9 Is a Stable Marker of Human Regulatory Macrophages

Riquelme, Paloma, Amodio, Giada, Macedo, Camila, Moreau, Aurelie, Obermajer, Nataša, Brochhausen, Christoph, Ahrens, Norbert , Kekarainen, Tuija, Fändrich, Fred, Cuturi, Cristina, Gregori, Silvia, Metes, Diana, Schlitt, Hans J., Thomson, Angus W., Geissler, Edward K. and Hutchinson, James A. (2017) DHRS9 Is a Stable Marker of Human Regulatory Macrophages. Transplantation 101 (11), pp. 2731-2738.

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Other URL: http://doi.org/10.1097/TP.0000000000001814


Abstract

Background. The human regulatory macrophage (Mreg) has emerged as a promising cell type for use as a cell-based adjunct immunosuppressive therapy in solid organ transplant recipients. In this brief report, dehydrogenase/reductase 9 (DHRS9) is identified as a robust marker of human Mregs. Methods. The cognate antigen of a mouse monoclonal antibody raised against human Mregs was identified as DHRS9 ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
10.1097/TP.0000000000001814DOI
Keywords:HUMAN DENDRITIC CELLS; RETINOIC ACID; SUPPRESSOR-CELLS; MYELOID CELLS; T-CELL; EXPRESSION; DIFFERENTIATION; TRANSPLANTATION; METABOLISM; ACTIVATION;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39597
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