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DHRS9 Is a Stable Marker of Human Regulatory Macrophages

Riquelme, Paloma ; Amodio, Giada ; Macedo, Camila ; Moreau, Aurelie ; Obermajer, Nataša ; Brochhausen, Christoph ; Ahrens, Norbert ; Kekarainen, Tuija ; Fändrich, Fred ; Cuturi, Cristina ; Gregori, Silvia ; Metes, Diana ; Schlitt, Hans J. ; Thomson, Angus W. ; Geissler, Edward K. ; Hutchinson, James A.



Abstract

Background. The human regulatory macrophage (Mreg) has emerged as a promising cell type for use as a cell-based adjunct immunosuppressive therapy in solid organ transplant recipients. In this brief report, dehydrogenase/reductase 9 (DHRS9) is identified as a robust marker of human Mregs. Methods. The cognate antigen of a mouse monoclonal antibody raised against human Mregs was identified as ...

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