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Actin assembly mechanisms at a glance

Rottner, Klemens , Faix, Jan, Bogdan, Sven, Linder, Stefan and Kerkhoff, Eugen (2017) Actin assembly mechanisms at a glance. Journal of Cell Science 130 (20), pp. 3427-3435.

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Other URL: http://doi.org/10.1242/jcs.206433


The actin cytoskeleton and associated motor proteins provide the driving forces for establishing the astonishing morphological diversity and dynamics of mammalian cells. Aside from functions in protruding and contracting cell membranes for motility, differentiation or cell division, the actin cytoskeleton provides forces to shape and move intracellular membranes of organelles and vesicles. To ...


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Item type:Article
Institutions:Medicine > Lehrstuhl für Neurologie
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Keywords:WISKOTT-ALDRICH-SYNDROME; FILAMENT BARBED-END; PRIMARY HUMAN MACROPHAGES; FOCAL ADHESION FORMATION; SYNDROME PROTEIN WASP; ARP2/3 COMPLEX; N-WASP; FILOPODIA FORMATION; STRESS FIBERS; CELL-MIGRATION; Actin cytoskeleton; Actin nucleation; Actin filament elongation; Myosin force generation; Membrane protrusion; Membrane contractions; Membrane trafficking; Rho-GTPase signalling
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39672
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