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Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition

Mysore, Raghavendra , Liebisch, Gerhard , Zhou, You, Olkkonen, Vesa M. and Nidhina Haridas, P.A. (2017) Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition. Chemistry and Physics of Lipids 207, pp. 246-252.

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Other URL: http://doi.org/10.1016/j.chemphyslip.2017.05.002


Abstract

Angiopoietin-like 8 (Angptl8) inhibits lipolysis in the circulation together with Angplt3 and controls post-prandial fat storage in white adipose tissue (WAT). It is strongly induced by insulin in vivo in WAT and in vitro in adipocytes. In this study we addressed the function of Angptl8 in adipocytes by its stable lentivirus-mediated knock-down in 3T3-L1 cells, followed by analyses of ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Identification Number:
ValueType
10.1016/j.chemphyslip.2017.05.002DOI
Keywords:TANDEM MASS-SPECTROMETRY; HIGH-THROUGHPUT QUANTIFICATION; INSULIN-RESISTANCE; LIPID-METABOLISM; ADIPOSE-TISSUE; PROTEIN; LEPTIN; BETATROPHIN; EXPRESSION; GLUCOSE; Angptl8; Lipidome; Lipid storage; Lipolysis; Plasmalogen; Triglyceride; Ether phospholipids
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39708
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