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Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma

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Kleo, K. ; Dimitrova, L. ; Oker, E. ; Tomaszewski, N. ; Berg, E. ; Taruttis, Franziska ; Engelmann, Julia C. ; Schwarzfischer, Philipp ; Reinders, Jörg ; Spang, Rainer ; Gronwald, Wolfram ; Oefner, Peter J. ; Hummel, Michael
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 24 Apr 2019 09:23


Background: MYC is a heterogeneously expressed transcription factor that plays a multifunctional role in many biological processes such as cell proliferation and differentiation. It is also associated with many types of cancer including the malignant lymphomas. There are two types of aggressive B-cell lymphoma, namely Burkitt lymphoma (BL) and a subgroup of diffuse large cell lymphoma (DLBCL), ...


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