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Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients

URN to cite this document:
urn:nbn:de:bvb:355-epub-401283
DOI to cite this document:
10.5283/epub.40128
Johannesen, Siw Wollebæk ; Budeus, Bettina ; Peters, Sebastian ; Iberl, Sabine ; Meyer, Anne-Louise ; Kammermaier, Tina ; Wirkert, Eva ; Bruun, Tim-Henrik ; Samara, Verena C. ; Schulte-Mattler, Wilhelm ; Herr, Wolfgang ; Schneider, Armin ; Grassinger, Jochen ; Bogdahn, Ulrich
Date of publication of this fulltext: 30 Apr 2019 08:00



Abstract

Objective: To evaluate safety, tolerability and feasibility of long-term treatment with Granulocyte-colony stimulating factor (G-CSF), a well-known hematopoietic stem cell factor, guided by assessment of mobilized bone marrow derived stem cells and cytokines in the serum of patients with amyotrophic lateral sclerosis (ALS) treated on a named patient basis. Methods: 36 ALS patients were treated ...

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