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Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients

Johannesen, Siw, Budeus, Bettina, Peters, Sebastian, Iberl, Sabine, Meyer, Anne-Louise, Kammermaier, Tina, Wirkert, Eva, Bruun, Tim-Henrik, Samara, Verena C., Schulte-Mattler, Wilhelm, Herr, Wolfgang, Schneider, Armin, Grassinger, Jochen and Bogdahn, Ulrich (2018) Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients. Frontiers in Neurology 9 (971), pp. 1-15.

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Date of publication of this fulltext: 30 Apr 2019 08:00

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Other URL: http://doi.org/10.3389/fneur.2018.00971


Abstract

Objective: To evaluate safety, tolerability and feasibility of long-term treatment with Granulocyte-colony stimulating factor (G-CSF), a well-known hematopoietic stem cell factor, guided by assessment of mobilized bone marrow derived stem cells and cytokines in the serum of patients with amyotrophic lateral sclerosis (ALS) treated on a named patient basis. Methods: 36 ALS patients were treated ...

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Item type:Article
Date:26 November 2018
Institutions:Medicine > Lehrstuhl für Neurologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3389/fneur.2018.00971DOI
Keywords:amyotrophic lateral sclerosis, granulocyte-colony stimulating factor, cytokines, hematopoietic stem and progenitor cells, HSPC, treatment
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40128
Owner only: item control page

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