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Effects of the Highly COX-2-Selective Analgesic NSAID Etoricoxib on Human Periodontal Ligament Fibroblasts during Compressive Orthodontic Mechanical Strain

Kirschneck, Christian, Küchler, Erika Calvano, Wolf, Michael, Spanier, Gerrit, Proff, Peter and Schröder, Agnes (2019) Effects of the Highly COX-2-Selective Analgesic NSAID Etoricoxib on Human Periodontal Ligament Fibroblasts during Compressive Orthodontic Mechanical Strain. Mediators of Inflammation 2019 (251495), pp. 1-14.

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Date of publication of this fulltext: 30 Apr 2019 10:55

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Other URL: http://doi.org/10.1155/2019/2514956


Abstract

Human periodontal ligament (hPDL) fibroblasts play a major role during periodontitis and orthodontic tooth movement, mediating periodontal inflammation, osteoclastogenesis, and collagen synthesis. The highly COX-2-selective NSAID etoricoxib has a favorable systemic side effect profile and high analgesic efficacy, particularly for orthodontic pain. In this in vitro study, we investigated possible ...

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Item type:Article
Date:10 March 2019
Institutions:Medicine > Lehrstuhl für Kieferorthopädie
Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1155/2019/2514956DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40146
Owner only: item control page

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