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New views on an old antibiotic: Effects of minocycline on innate versus stress-induced behavioural, immunological, and microbiome changes

Schmidtner, Anna-Kristina (2019) New views on an old antibiotic: Effects of minocycline on innate versus stress-induced behavioural, immunological, and microbiome changes. PhD, Universität Regensburg.

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Date of publication of this fulltext: 06 Jun 2019 08:46

Abstract (English)

Excessive states of sensations like fear, anxiety, risk assessment, and others, and the resulting psychiatric disorders, render humans incapable of directing their own life. Psychiatric disorders like generalized anxiety disorder (GAD) and major depressive disorder (MDD) are the sixth and the leading cause of disability worldwide, respectively, and represent a major burden for both patients and ...

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Translation of the abstract (German)

Die Basis psychischer Erkrankungen sind grundlegende und evolutionär essentielle Emotionen, die in einem exzessiven und unangepassten Zustand ein pathologisches Ausmaß annehmen. Dadurch sind Patienten oftmals nicht mehr in der Lage, ihr Leben in geregelten Bahnen zu führen. Die generalisierte Angststörung (GAD) und Depressionen (MDD) zählen zu den wichtigsten Gründen für Erwerbsunfähigkeit, wobei ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:6 June 2019
Referee:Prof. Dr. Inga D. Neumann
Date of exam:23 May 2019
Institutions:Biology, Preclinical Medicine > Institut für Zoologie > Tierphysiologie/Neurobiologie (Prof. Dr. Inga Neumann)
Keywords:Minocycline Depression Microglia Microbiome Microbiome-gut-brain axis Chronic subordinate colony housing
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40253
Owner only: item control page

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