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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-404647
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.40464
Zusammenfassung
We have recently discovered that cancer cells take up extracellular citrate through plasma membrane citrate transporter (pmCiC) and advantageously use citrate for their metabolism. Citrate uptake can be blocked with gluconate and this results in decreased tumor growth and altered metabolic characteristics of tumor tissue. Interestingly, gluconate, considered to be physiologically neutral, is ...
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