Go to content
UR Home

Inhibition of heat shock protein 90 with AUY922 represses tumor growth in a transgenic mouse model of islet cell neoplasms

URN to cite this document:
urn:nbn:de:bvb:355-epub-407526
Fendrich, Volker ; Wichmann, Sven ; Wiese, Dominik ; Waldmann, Jens ; Lauth, Matthias ; Rexin, P. ; Lopez, C.L. ; Schlitt, Hans J. ; Bartsch, D. ; Lang, Sven A.
[img]
Preview
PDF - Published Version
(1MB)
Date of publication of this fulltext: 02 Oct 2019 13:12


Abstract

Background: This study was designed to evaluate the role of heat shock protein 90 (HSP90) in tumor progression of murine islet cell tumors. Blockade of HSP90 has recently been proposed as a therapeutic target, but effects in models of islet cell tumors with AUY922, a newly developed HSP90 inhibitor, have not been examined. Material and Methods: The carcinoid cell line BON-1 and the HSP90 ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons