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Hypoxia Induces the Expression of Transketolase-Like 1 in Human Colorectal Cancer

Bentz, S., Cee, A. and Endlicher, E. (2013) Hypoxia Induces the Expression of Transketolase-Like 1 in Human Colorectal Cancer. Digestion 88, pp. 182-192.

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Date of publication of this fulltext: 10 Oct 2019 07:11

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Other URL: https://www.karger.com/Article/FullText/355015


Abstract

Background and Aims: Transketolase-like (TKTL) 1 is one of the key enzymes for anaerobic sugar degradation even in the presence of oxygen (aerobic glycolysis). Transketolase-dependent reactions supply malignant tumors with ribose and NADPH. Therefore, TKTL1 activity could be crucial for tumor proliferation and survival. The aim of the study was to evaluate the expression of TKTL1 in colorectal ...

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Item type:Article
Date:2013
Additional Information (public):OA-Komponente aus Allianzlizenz
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1159/000355015DOI
Keywords:Colorectal cancer, Aerobic glycolysis, Hypoxia, Pentose phosphate way
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40796
Owner only: item control page

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