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Disruption of Endogenous Purinergic Signaling Inhibits Vascular Endothelial Growth Factor- and Glutamate-Induced Osmotic Volume Regulation of Muller Glial Cells in Knockout Mice

Grosche, Antje, Pannicke, Thomas, Chen, Ju, Reichenbach, A. and Bringmann, A. (2013) Disruption of Endogenous Purinergic Signaling Inhibits Vascular Endothelial Growth Factor- and Glutamate-Induced Osmotic Volume Regulation of Muller Glial Cells in Knockout Mice. Ophthalmic Research 50, pp. 209-214.

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Date of publication of this fulltext: 10 Oct 2019 07:23

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Other URL: https://www.karger.com/Article/FullText/354082


Abstract

Background/Aims: Osmotic swelling of Müller cells is a common phenomenon in animal models of ischemic and diabetic retinopathies. Müller cells possess a swelling-inhibitory purinergic signaling cascade which can be activated by various receptor ligands including vascular endothelial growth factor (VEGF) and glutamate. Here, we investigated whether deletion of P2Y1 (P2Y1R) and adenosine A1 ...

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Item type:Article
Date:2013
Additional Information (public):OA-Komponente aus Allianzlizenz
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1159/000354082DOI
Keywords:Osmotic swelling; Muller cell; Vascular endothelial growth factor; Glutamate; Calcium
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40797
Owner only: item control page

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