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The Impact of Altered Gravity and Vibration on Endothelial Cells During a Parabolic Flight

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Wehland, M. ; Ma, Xiao ; Braun, M. ; Hauslage, J. ; Hemmersbach, R. ; Bauer, Johann ; Grosse, Jirka ; Infanger, M. ; Grimm, Daniela
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Date of publication of this fulltext: 21 Oct 2019 08:57


Background: Endothelial cells (EC) cultured under altered gravity conditions show a cytoskeletal disorganization and differential gene expression (short-term effects), as well as apoptosis in adherently growing EC or formation of tubular 3D structures (long-term effects). Methods: Investigating short-term effects of real microgravity, we exposed EC to parabolic flight maneuvers and analysed them ...


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