Scharl, M., Leucht, K., Frey-Wagner, I., Zeitz, J., Hausmann, M., Fischbeck, A., Liebisch, Gerhard 
, Schmitz, Gerd and Rogler, Gerhard
(2011)
Knock-Out of beta-Glucosidase 2 Has No Influence on Dextran Sulfate Sodium-Induced Colitis.
Digestion 84, pp. 156-167.
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Other URL: https://www.karger.com/Article/FullText/327380
Abstract
Background/Aims: The non-lysosomal glucosylceramidase, β-glucosidase (Gba2), hydrolyzes glucosylceramide to glucose and ceramide (Cer). Cer is a potent second-messenger lipid that plays an important role in signaling cascades involved in apoptosis. The aim of this study was to investigate whether Gba2 knock-out (Gba2–/–) affects the extent of dextran sulfate sodium (DSS)-induced colitis in mice. ...
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| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 2011 | ||||
| Additional Information (public): | OA-Komponente aus Allianzlizenz | ||||
| Institutions: | Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin | ||||
| Identification Number: |
| ||||
| Keywords: | Apoptosis, Cell regeneration, β-Glucosidase, DSS colitis, Ceramide | ||||
| Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 40902 |
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