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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-409028
- DOI to cite this document:
- 10.5283/epub.40902
Abstract
Background/Aims: The non-lysosomal glucosylceramidase, beta-glucosidase (Gba2), hydrolyzes glucosylceramide to glucose and ceramide (Cer). Cer is a potent second-messenger lipid that plays an important role in signaling cascades involved in apoptosis. The aim of this study was to investigate whether Gba2 knock-out (Gba2(-/-)) affects the extent of dextran sulfate sodium (DSS)-induced colitis in ...

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