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Fifty-kDa Hyaluronic Acid Upregulates Some Epidermal Genes without Changing TNF-α Expression in Reconstituted Epidermis

Farwick, M., Gauglitz, G., Pavicic, T., Köhler, T., Wegmann, M., Schwach-Abdellaoui, K., Malle, D., Tarabin, V., Schmitz, Gerd and Korting, H. C. (2011) Fifty-kDa Hyaluronic Acid Upregulates Some Epidermal Genes without Changing TNF-α Expression in Reconstituted Epidermis. Skin Pharmacology and Physiology 24, pp. 210-217.

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Date of publication of this fulltext: 06 Nov 2019 09:59

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Other URL: https://www.karger.com/Article/Abstract/324296


Abstract

Background: Due to its strong water binding potential, hyaluronic acid (HA) is a well-known active ingredient for cosmetic applications. However, based on its varying molecular size, skin penetration of HA may be limited. Recent studies have demonstrated that low-molecular-weight HA (LMW HA) may show a certain proinflammatory activity. We thus aimed to characterize an LMW-sized HA molecule that ...

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Item type:Article
Date:2011
Additional Information (public):OA-Komponente aus Allianzlizenz
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Identification Number:
ValueType
10.1159/000324296DOI
Keywords:Hyaluronic acid, Skin penetration, Anti-wrinkle effect, Skin inflammation
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40996
Owner only: item control page

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