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Impact of the Sensory and Sympathetic Nervous System on Fracture Healing in Ovariectomized Mice

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Niedermair, Tanja ; Straub, Rainer H. ; Brochhausen, Christoph ; Grässel, Susanne
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 07 Feb 2020 10:42


The peripheral nervous system modulates bone repair under physiological and pathophysiological conditions. Previously, we reported an essential role for sensory neuropeptide substance P (SP) and sympathetic nerve fibers (SNF) for proper fracture healing and bone structure in a murine tibial fracture model. A similar distortion of bone microarchitecture has been described for mice lacking the ...


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