Increased Expression of RUNX1 in Liver Correlates with NASH Activity Score in Patients with Non-Alcoholic Steatohepatitis (NASH)

URN to cite this document:: urn:nbn:de:bvb:355-epub-415303
DOI to cite this document:: 10.5283/epub.41530

Kaur, Savneet ; Rawal, Preety ; Siddiqui, Hamda ; Rohilla, Sumai ; Sharma, Shvetank ; Tripathi, Dinesh M. ; Baweja, Sukriti ; Hassan, Mohsin ; Vlaic, Sebastian ; Guthke, Reinhard ; Thomas, Maria ; Dayoub, Rania

; Bihari, Chaggan ; Sarin, Shiv K. ; Weiss, Thomas S.

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Date of publication of this fulltext: 07 Feb 2020 16:20

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Abstract

Given the important role of angiogenesis in liver pathology, the current study investigated the role of Runt-related transcription factor 1 (RUNX1), a regulator of developmental angiogenesis, in the pathogenesis of non-alcoholic steatohepatitis (NASH). Quantitative RT-PCRs and a transcription factor analysis of angiogenesis-associated differentially expressed genes in liver tissues of healthy ...