| License: Creative Commons Attribution 4.0 PDF - Published Version (756kB) |
- URN to cite this document:
- urn:nbn:de:bvb:355-epub-415653
- DOI to cite this document:
- 10.5283/epub.41565
Abstract
Isosorbide-2-carbamates-5-aryl esters are highly potent and very selective butyrylcholinesterase inhibitors. The objective of the present work was to address the hypothesis that the isosorbide-aryl-5-ester group could be replaced with an antioxidant functionality while maintaining inhibitor effects and selectivity. We successfully incorporated ferulic acid or lipoic acid groups producing potent ...

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