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Lack of a retinal phenotype in a Syne-2/Nesprin-2 knockout mouse model

URN to cite this document:
urn:nbn:de:bvb:355-epub-415861
Falk, Nathalie ; Joachimsthaler, A. ; Kessler, K.
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Date of publication of this fulltext: 20 Feb 2020 09:38


Abstract

Syne-2 (also known as Nesprin-2) is a member of a family of proteins that are found primarily in the outer nuclear membrane, as well as other subcellular compartments. Syne-2 contains a C-terminal KASH transmembrane domain and is part of a protein network that associates the nuclear envelope to the cytoskeleton via the binding to actin filaments. Syne-2 plays a role in nuclear migration, nuclear ...

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