Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma

URN to cite this document:: urn:nbn:de:bvb:355-epub-415899
DOI to cite this document:: 10.5283/epub.41589

Cigliano, Antonio

; Pilo, M. G. ; Mela, M. ; Evert, Matthias ; Calvisi, Diego F. ; Utpatel, Kirsten

; ; ; ;

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Date of publication of this fulltext: 13 Feb 2020 13:52

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Abstract

Background and Objectives: Intrahepatic cholangiocarcinoma (iCCA) is a pernicious tumor characterized by a dismal outcome and scarce therapeutic options. To substantially improve the prognosis of iCCA patients, a better understanding of the molecular mechanisms responsible for development and progression of this disease is imperative. In the present study, we aimed at elucidating the role of the ...